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I haven't personally used it, but it appears that the ROS API is well-written and well-supported by the actual manufacturer/designer.
It appears that all of the information from the robot base is brought out on various message types. I don't know what kind of "flexibility" that you are looking for, but you could probably use the documented API and extend it to anything that you could possibly need.
I would imagine that any computer supported by ROS and clearpath would serve to work with the platform.